Director, Supply Chain Planning
Company: Dyne Therapeutics
Location: Waltham
Posted on: July 8, 2025
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Job Description:
Company Overview: Dyne Therapeutics is focused on delivering
functional improvement for people living with genetically driven
neuromuscular diseases. We are developing therapeutics that target
muscle and the central nervous system (CNS) to address the root
cause of disease. The company is advancing clinical programs for
myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy
(DMD), and preclinical programs for facioscapulohumeral muscular
dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to
deliver functional improvement for individuals, families and
communities. Learn more https://www.dyne-tx.com/ , and follow us on
X , LinkedIn and Facebook . Role Summary: The Director of Supply
Chain Planning is responsible for end-to-end inventory and
production planning across Dyne’s external supply network. This
includes long-range planning (LRP), ensuring uninterrupted clinical
supply, and supporting commercial launch readiness through
scenario-based planning and risk assessments. This strategic role
is critical in executing current planning activities and shaping
future supply chain capabilities. The Director collaborates
cross-functionally with Process Development, Research, CMC,
Quality, Clinical Operations, and Commercial teams. It is an
opportunity to help shape the future of Dyne’s supply chain
function during a critical period of growth and innovation. This
role is based in Waltham, MA without the possibility of being fully
remote. Primary Responsibilities Include: Collaborate with
cross-functional partners in CMC, Logistics, Quality, Clinical
Operations, and Commercial to develop and maintain a reliable
demand and supply plan, ensure uninterrupted product availability
for patients, support commercial readiness, and align with the
company’s business objectives. Maintain an understanding of
external manufacturing site capacities, capabilities, and supply
risks. Identify and implement opportunities to optimize supply
chain processes and drive efficiencies. Lead scenario planning to
evaluate alternative demand and supply assumptions and inform risk
mitigation strategies. Lead monthly demand and supply planning
meetings with cross functional team members as part of our drive to
a formal Integrated Business Planning / Sales and Operations
Planning process. Perform analysis of Dyne portfolio, including
inventory projections, supply performance and risks. Integrate with
other global planning processes to monitor key performance
indicators (KPIs) and analyze supply chain data to identify
opportunities for improvement and cost savings. Author Supply
Chain-related standard operating procedures (SOPs) and work
instructions. Manage relationships with third-party suppliers and
vendors to ensure timely delivery of materials and components.
Ensure compliance with regulatory requirements and quality
standards in supply chain operations. Education and Skills
Requirements: Bachelor’s degree in Supply Chain, Business,
Engineering, or a related field; advanced degree preferred. Minimum
of 10 years of relevant experience in a biotech, pharmaceutical, or
life sciences environment. Ability to effectively plan, prioritize,
execute, follow up and anticipate challenges. Experience managing
complex schedules and priorities in dynamic pharmaceutical, biotech
or related environments. Ability to work, influence, and gain
agreement across multiple functions. Strong analytical, problem
solving and critical thinking skills. Strong knowledge of supply
chain best practices, inventory management, and demand forecasting.
Proficiency in advanced Excel functions and familiarity with
planning and analytics tools such as Smartsheet, Visio, ERP systems
(e.g., SAP, Oracle), and Power BI. Collaborative work style to be
part of a team to identify process gaps and develop solutions.
Excellent interpersonal, verbal, and written communication skills.
Experience in supply chain, drug development, project management,
and/or pharmaceutical manufacturing/packaging. In-depth working
knowledge of regulations relating to clinical manufacturing,
packaging and distribution activities (CGMP, GCP). APICS or CSCMP
certification a plus. LI-Onsite The statements contained herein
reflect general details as necessary to describe the principles
functions for this job, the level of knowledge and skill typically
required, and the scope of responsibility, but should not be
considered an all-inclusive listing of work requirements.
Individuals may perform other duties as assigned, including work in
other functional areas to cover absences or relief, to equalize
peak work periods or otherwise balance workload. This description
is not intended to be constructed as an exhaustive list of duties,
responsibilities, or requirements for the position. This position
may change or assume additional duties at any time. The employee
may be requested to perform different or additional duties as
assigned. All Employees are expected to adhere to all company
policies and act as a role model for company values. Dyne
Therapeutics is an equal opportunity employer and will not
discriminate against any employee or applicant on the basis of age,
color, disability, gender, national origin, race, religion, sexual
orientation, veteran status, or any classification protected by
federal, state, or local law.
Keywords: Dyne Therapeutics, Arlington , Director, Supply Chain Planning, Retail - All , Waltham, Massachusetts